Received Offspring - Medical research into Down's syndrome

Dr Elizabeth Fisher, Institute of Neurology, University College London

There are a number of research teams currently worldwide who are investigating specific areas that contribute in part to the Down's syndrome condition. Dr. Elizabeth Fisher's team at the Institute of Neurology, University College London, has helped the work of these various teams. Dr. Fisher's team in 2005, were able to transfer the extra chromosome within Chromosome 21 found within humans into the mouse model. This will enable research teams to obtain assured and reliable findings from their research, more so than from the mouse chromosome. Professor Timothy Bliss of the Research Institute, Mill Hill, London will assist the applicant in his research to correctly illustrate the hippocampus through his yoke-like apparatus.

The Artist has met with Dr. Elizabeth Fisher at the Institute of Neurology, discussed her research and toured the research laboratories. Dr. Fisher's assistance to this project is ongoing.

A diagram trying to illustrate how certain strains of mice might be studied in order to find out which genes underlie specific traits that arise in Down's syndrome. Drawn during Dr. Elizabeth Fisher's meeting with the artist.© Dr Elizabeth Fisher, 7 June 2006, biro ink.

Image of the human hippocampus © Prof. Sebastian Brandner, Chair of Neuropathology, Division of Neuropathology andDept. of Neurodegenerative Disease, Institute of Neurology, Queen Square London WC1N 3BG,

New Centre for Down's syndrome, Stanford University - Professor William Mobley's Team

At their meeting at the 'Bright Beginnings' conference, Institute of Child Health, London, 1 April 2006 organised by the Down's syndrome Research Foundation; Professor William Mobley discussed his research with the artist. Professor Mobley illustrated his research on the Hippocampus, by way of sketches drawn during this meeting.

Sketch showing the hippocampus in section and the brain circuit within: Dentate Gyrus, bottom left and neurons CA3 and CA1. © Prof. William Mobley & Charles Walker Hazzard

Sketch showing the hippocampus, its location in the human brain and a sectional view of the hippocampus, lower right. © Prof. William Mobley & Charles Walker Hazzard